OncoTrace™ BOB.1 – Recombinant Antibody for Lymphoma Diagnosis
Accuracy and Consistency in Hematopathological Diagnosis
OncoTrace™ BOB.1 (Clone QR072) is a recombinant rabbit monoclonal antibody developed for the specific detection of the BOB.1 nuclear marker in FFPE tissue samples. Produced in vitro with advanced technology, it offers high sensitivity, intense nuclear signal and very low background, guaranteeing reliable and consistent batch-to-batch results – an essential differentiator for the subclassification of lymphomas.
Why choose OncoTrace™ BOB.1?
- High diagnostic accuracy: Ideal for B-cell lymphomas and Hodgkin’s lymphoma.
- Clean nuclear staining: Facilitates interpretation and secure reports.
- Absolute consistency: Recombinant production eliminates variations between batches.
- Compatible with automation: Validated for the main IHQ platforms.
- Cruelty Free: Ethical production, 100% animal-free.
Main applications
Indicated for the detection of BOB.1 protein in B cells (germinal center, mantle and plasma cells), aiding in the diagnosis and subclassification of non-Hodgkin’s lymphoma and Hodgkin’s lymphoma.
Advantages of the OncoTrace™ Recombinant Antibody
| Features | OncoTrace™ Recombinant | Traditional hybridoma |
|---|---|---|
| Origin | In vitro production (without animals) | Production in mice |
| Reliability | Identical performance between batches | Frequent variations |
| Specificity | High affinity, minimal background | Higher risk of cross-reactivity |
| Standardization | Total control and optimization | Subject to genetic drift |
Technical Specifications
- Clone: QR072
- Host: Rabbit (IgG)
- Immunogen: Synthetic peptide of the human protein BOB.1
- Application: Immunohistochemistry (IHC) on FFPE tissues
- Location: Nuclear
- Recommended dilution (Concentrate): 1:100 – 1:200
- Positive Control: Tonsil, Lymphoma
- Available formats:
- Concentrate: 0.1 ml, 1 ml
- Ready for use: 1 ml, 6 ml
- Storage: 2°C – 8°C (stable until expiration date)
Frequently Asked Questions (FAQ)
What is the OncoTrace™ BOB.1 antibody used for?
It is used for the diagnosis and subclassification of B-cell lymphomas and Hodgkin’s lymphoma by detecting the BOB.1 nuclear protein in FFPE tissues.
What are the advantages of the recombinant format?
It guarantees absolute consistency between batches, eliminating re-optimizations and saving time and resources.
Is it compatible with automation?
Yes. OncoTrace™ BOB.1 has been validated for the main automated IHQ platforms on the market.
How to store it?
Keep between 2°C and 8°C, stable until expiration date even after opening.
Raise the Standard of Your Diagnosis
Invest in recombinant technology and get more reliable reports. Request a quote or order your sample of OncoTrace™ BOB.1 (QR072) now.
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