OncoTrace™ Desmina (QR026) – Recombinant Antibody for Tumor Diagnosis
High Accuracy in Detecting Tumors with Myxoid Origin
OncoTrace™ Desmina (Clone QR026) is a recombinant rabbit monoclonal antibody developed for the qualitative detection of the Desmina protein in FFPE tissues. Produced in vitro with state-of-the-art technology, it offers high specificity, clear cytoplasmic staining and very low background, guaranteeing batch-to-batch reproducibility and consistency for safer diagnoses in tumors of muscular origin.
Why Choose OncoTrace™ Desmina?
- High Specificity: Ideal for identifying tumors of myxoid origin and differentiating mesothelioma from carcinoma.
- Clear cytoplasmic staining: Facilitates interpretation and reduces the risk of false positives.
- Recombinant Production: Consistent performance between batches and elimination of common variations in hybridomas.
- Compatible with Automation: Validated for use manually or on automated IHQ platforms.
- Cruelty Free: In vitro production without the use of animals.
Diagnostic Applications
Desmin is a structural protein of the intermediate filament type, found in smooth and striated muscle. The OncoTrace™ Desmin antibody is used in immunohistochemistry (IHC) to help identify tumors with a myxoid origin and differentiate between mesothelioma and carcinoma.
Comparison: Recombinant vs. hybridoma
| Features | OncoTrace™ Recombinant | Traditional hybridoma |
|---|---|---|
| Origin | Produced in vitro (without animals) | Produced in mice |
| Reliability | Identical performance between batches | Frequent variation |
| Specificity | High affinity, minimal background | Higher risk of cross-reactivity |
| Standardization | Fully controlled | Subject to genetic drift |
Technical Specifications
- Clone: QR026
- Host: Rabbit (IgG)
- Immunogen: Synthetic peptide of the human protein Desmin
- Application: Immunohistochemistry (IHC) on FFPE tissues
- Cellular Location: Cytoplasmic
- Recommended dilution (Concentrate): 1:100 – 1:200
- Positive Control: Skeletal muscle
- Available formats:
- Concentrate: 0.1 ml, 1 ml
- Ready for use: 1 ml, 6 ml
- Storage: 2°C – 8°C (stable until expiration date)
Frequently Asked Questions (FAQ)
What is the OncoTrace™ Desmina antibody used for?
It helps detect tumors of muscular origin and differentiate between mesothelioma and carcinoma by marking the Desmin protein in FFPE tissues.
What are the advantages of the recombinant format?
It guarantees absolute consistency between batches, eliminating the need for re-optimizations, saving time and resources.
Is the product compatible with automation?
Yes. OncoTrace™ Desmina is validated for the main automated IHQ platforms on the market.
How to store it?
Keep between 2°C and 8°C. Product stable until expiry date even after opening.
Trust and Standardization for Safer Diagnostics
Raise the standard of your diagnostics with recombinant technology. Request a quote or ask for a sample of OncoTrace™ Desmina (QR026) now.
Reviews
There are no reviews yet.