OncoTrace™ p53 (QR025) – Recombinant Antibody for Oncological Diagnosis
High Accuracy in Detecting the Tumor Marker p53
OncoTrace™ p53 (Clone QR025) is a recombinant rabbit monoclonal antibody developed for the specific detection of the nuclear marker p53 in FFPE tissue samples. Produced in vitro with advanced technology, it offers high sensitivity, clear nuclear staining and absolute batch-to-batch consistency, guaranteeing accurate diagnoses in various neoplasms.
Why choose OncoTrace™ p53?
- Essential Tumor Marker: p53 is a tumor suppressor gene, frequently mutated in more than 50% of human cancers.
- High Specificity: Ideal for detecting colon, breast, lung, prostate and ovarian carcinomas.
- Recombinant Production: Reproducible results and elimination of typical hybridoma variations.
- Compatible with Automation: Validated for use manually or in automated IHQ systems.
- Cruelty Free: In vitro production without the use of animals.
Diagnostic Applications
The OncoTrace™ p53 antibody helps identify tumor cells with overexpression of the p53 protein, which is common in carcinomas and aggressive tumors. Its interpretation should be carried out by experienced pathologists within the clinical context of the patient.
Comparison: Recombinant vs. hybridoma
| Features | OncoTrace™ Recombinant | Traditional hybridoma |
|---|---|---|
| Origin | Produced in vitro (without animals) | Produced in mice |
| Reliability | Identical performance between batches | Frequent variation |
| Specificity | High affinity, minimal background | Higher risk of cross-reactivity |
| Standardization | Fully controlled | Subject to genetic drift |
Technical Specifications
- Clone: QR025
- Host: Rabbit (IgG)
- Immunogen: Synthetic peptide of the human protein p53
- Application: Immunohistochemistry (IHC) on FFPE tissues
- Cellular Location: Nuclear
- Recommended dilution (Concentrate): 1:100 – 1:200
- Positive Control: Colon or breast carcinoma
- Available formats:
- Concentrate: 0.1 ml, 1 ml
- Ready for use: 1 ml, 6 ml
- Storage: 2°C – 8°C (stable until expiration date)
Frequently Asked Questions (FAQ)
What is the OncoTrace™ p53 antibody used for?
It is used to detect the p53 protein in FFPE tissues, helping to identify mutations associated with tumor progression.
What are the advantages of the recombinant format?
It guarantees high standardization and consistency between batches, reducing errors and saving validation time.
Is the product compatible with automation?
Yes. OncoTrace™ p53 has been validated for use on automated platforms and manual IHQ protocols.
How to store it?
Keep between 2°C and 8°C. Product stable until expiry date even after opening.
Reliability for High Complexity Diagnostics
Invest in recombinant technology for accurate results. Request a quote or order your sample of OncoTrace™ p53 (QR025) now.
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