OncoTrace\u2122 PMS2 (Clone QR009)<\/strong> is a recombinant rabbit monoclonal antibody (IgG)<\/strong>, developed for the nuclear detection of the PMS2 protein<\/strong> in FFPE<\/strong> tissues. The PMS2 protein is an essential part of the DNA mismatch repair (MMR) system<\/strong>, acting in conjunction with MLH1. The absence of its expression is associated with microsatellite instability (MSI)<\/strong>, a central feature in Lynch syndrome (HNPCC)<\/strong> and various tumors, including colorectal and endometrial cancer. <\/p>\n OncoTrace\u2122 PMS2<\/strong> helps diagnose deficiencies in the MMR system<\/strong> and is an essential part of assessing microsatellite instability<\/strong>. Its integrated use with the OncoTrace\u2122 MLH1, MSH2 and MSH6 antibodies allows for greater precision in screening for Lynch syndrome<\/strong> and in diagnosing tumors with an MSI pattern. <\/p>\n It is used to assess microsatellite instability (MSI)<\/strong> and to screen for Lynch syndrome<\/strong>, as well as helping to diagnose colorectal and endometrial tumors.<\/p>\n The recombinant format offers maximum standardization, reproducible results and elimination of batch-to-batch variability<\/strong>, increasing diagnostic reliability.<\/p>\n Yes. OncoTrace\u2122 PMS2 is validated for use on automated platforms<\/strong> and in manual IHQ protocols. <\/p>\n Keep between 2\u00b0C and 8\u00b0C. Product stable until expiry date even after opening. <\/p>\n Strengthen cancer screening with recombinant technology.<\/strong> Request your quote or sample of OncoTrace\u2122 PMS2 (QR009)<\/strong> now.<\/p>\n","protected":false},"excerpt":{"rendered":" OncoTrace\u2122 PMS2 (QR009) \u2013 Recombinant Antibody for Microsatellite Instability Diagnosis High Reliability in Detecting MMR System Deficiencies OncoTrace\u2122 PMS2 (Clone QR009) is a recombinant rabbit monoclonal antibody (IgG), developed for the nuclear detection of the PMS2 protein in FFPE tissues. The PMS2 protein is an essential part of the DNA mismatch repair (MMR) system, acting…<\/p>\n","protected":false},"featured_media":16528,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[771],"product_tag":[751,774,458,460,459,775,773,772],"class_list":{"0":"post-17355","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-oncotrace-recombinant-antibodies","7":"product_tag-antibody","8":"product_tag-clone-en","9":"product_tag-easypath-en","10":"product_tag-ihc","11":"product_tag-immunohistochemistry","12":"product_tag-oncology","13":"product_tag-oncotrace-en","14":"product_tag-recombinant","16":"first","17":"instock","18":"shipping-taxable","19":"purchasable","20":"product-type-variable","21":"col-xs-6 col-sm-4","22":"col-md-3 col-lg-2","23":"un-6-cols"},"_links":{"self":[{"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product\/17355","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/comments?post=17355"}],"version-history":[{"count":0,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product\/17355\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/media\/16528"}],"wp:attachment":[{"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/media?parent=17355"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product_brand?post=17355"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product_cat?post=17355"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product_tag?post=17355"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Why choose OncoTrace\u2122 PMS2?<\/h2>\n
\n
Diagnostic Applications<\/h2>\n
Comparison: Recombinant vs. hybridoma<\/h2>\n
\n\n
\n \nFeatures<\/th>\n OncoTrace\u2122 Recombinant<\/th>\n Traditional hybridoma<\/th>\n<\/tr>\n<\/thead>\n \n \n Origin<\/strong>\n<\/td>\n Produced in vitro (without animals)<\/td>\n Produced in mice<\/td>\n<\/tr>\n \n \n Reliability<\/strong>\n<\/td>\n Identical performance between batches<\/td>\n Frequent variation<\/td>\n<\/tr>\n \n \n Specificity<\/strong>\n<\/td>\n High affinity, minimal background<\/td>\n Higher risk of cross-reactivity<\/td>\n<\/tr>\n \n \n Standardization<\/strong>\n<\/td>\n Fully controlled<\/td>\n Subject to genetic drift<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Technical Specifications<\/h2>\n
\n
\n
Frequently Asked Questions (FAQ)<\/h2>\n
What is the OncoTrace\u2122 PMS2 antibody used for?<\/h3>\n
What are the advantages of the recombinant format?<\/h3>\n
Is the product compatible with automation?<\/h3>\n
How to store it?<\/h3>\n
Confidence in High Complexity Diagnostics<\/h2>\n