{"id":17360,"date":"2025-08-21T23:13:13","date_gmt":"2025-08-22T02:13:13","guid":{"rendered":"https:\/\/easypath.com.br\/loja\/uncategorized\/oncotrace-pax-8-clone-qr016\/"},"modified":"2026-04-20T17:56:18","modified_gmt":"2026-04-20T20:56:18","slug":"oncotrace-pax-8-clone-qr016","status":"publish","type":"product","link":"https:\/\/easypath.com.br\/en\/produto\/oncotrace-pax-8-clone-qr016\/","title":{"rendered":"Oncotrace PAX-8, Clone QR016"},"content":{"rendered":"<h1>OncoTrace\u2122 PAX8 (QR016) \u2013 Recombinant Antibody for the Diagnosis of Renal, Ovarian, Endometrial and Thyroid Tumors<\/h1>\n<h2>High Specificity in Tumors of M\u00fcllerian, Renal and Thyroid Origin<\/h2>\n<p><strong>OncoTrace\u2122 PAX8 (Clone QR016)<\/strong> is a <strong>recombinant rabbit monoclonal antibody (IgG)<\/strong>, developed for the <strong>nuclear detection of the PAX8 protein<\/strong> in <strong>FFPE<\/strong> tissues. PAX8 belongs to the Paired Box family of transcription factors and is essential in the embryonic development of <strong>kidneys, M\u00fcllerian organs and the thyroid<\/strong>. Its restricted expression makes it a highly sensitive and specific marker for tumors originating in these tissues.  <\/p>\n<h2>Why choose the OncoTrace\u2122 PAX8?<\/h2>\n<ul>\n<li><strong>Critical Marker:<\/strong> PAX8 is present in <strong>ovarian (71-99%)<\/strong>, <strong>thyroid (~90%)<\/strong>, <strong>endometrial (84-98%)<\/strong> and <strong>renal carcinoma (~90%) carcinomas<\/strong>.<\/li>\n<li><strong>High Specificity:<\/strong> Excellent for distinguishing gynecological and renal tumors from metastatic neoplasms from other sites.<\/li>\n<li><strong>Recombinant Production:<\/strong> Stable performance, <strong>no variation between batches<\/strong>.<\/li>\n<li><strong>Compatible with Automation:<\/strong> Validated in manual protocols and automated IHQ platforms.<\/li>\n<li><strong>Cruelty Free:<\/strong> Produced in vitro, without the use of animals.<\/li>\n<\/ul>\n<h2>Diagnostic Applications<\/h2>\n<p><strong>OncoTrace\u2122 PAX8<\/strong> is indicated for the evaluation of tumors of <strong>M\u00fcllerian, renal and thyroid<\/strong> origin, helping to differentiate primary carcinomas of these organs from metastases. It is an essential marker in diagnostic panels for <strong>ovarian, endometrial and renal tumors<\/strong>. <\/p>\n<h2>Comparison: Recombinant vs. hybridoma<\/h2>\n<table style=\"border-collapse: collapse; border: 1px solid black;\" border=\"1\">\n<thead>\n<tr>\n<th>Features<\/th>\n<th>OncoTrace\u2122 Recombinant<\/th>\n<th>Traditional hybridoma<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\n  <strong>Origin<\/strong>\n<\/td>\n<td>Produced in vitro (without animals)<\/td>\n<td>Produced in mice<\/td>\n<\/tr>\n<tr>\n<td>\n  <strong>Reliability<\/strong>\n<\/td>\n<td>Identical performance between batches<\/td>\n<td>Frequent variation<\/td>\n<\/tr>\n<tr>\n<td>\n  <strong>Specificity<\/strong>\n<\/td>\n<td>High affinity, minimal background<\/td>\n<td>Higher risk of cross-reactivity<\/td>\n<\/tr>\n<tr>\n<td>\n  <strong>Standardization<\/strong>\n<\/td>\n<td>Fully controlled<\/td>\n<td>Subject to genetic drift<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Technical Specifications<\/h2>\n<ul>\n<li><strong>Clone:<\/strong> QR016<\/li>\n<li><strong>Host:<\/strong> Rabbit (IgG)<\/li>\n<li><strong>Immunogen:<\/strong> Synthetic peptide of the human protein PAX8<\/li>\n<li><strong>Application:<\/strong> Immunohistochemistry (IHC) on FFPE tissues<\/li>\n<li><strong>Cellular Location:<\/strong> Nuclear<\/li>\n<li><strong>Recommended dilution (Concentrate):<\/strong> 1:100 \u2013 1:200<\/li>\n<li><strong>Positive Control:<\/strong> Kidney (renal tubules), fallopian tube, endometrium or ovarian carcinoma<\/li>\n<li><strong>Available volumes:<\/strong>\n<ul>\n<li>Concentrate: 0.1 ml, 1 ml<\/li>\n<li>Ready for use: 1 ml, 6 ml<\/li>\n<\/ul>\n<\/li>\n<li><strong>Storage:<\/strong> 2\u00b0C \u2013 8\u00b0C (stable until expiration date)<\/li>\n<\/ul>\n<h2>Frequently Asked Questions (FAQ)<\/h2>\n<h3>What is the OncoTrace\u2122 PAX8 antibody used for?<\/h3>\n<p>It is used to identify tumors of <strong>M\u00fcllerian, renal and thyroid<\/strong> origin, differentiating them from metastases from other sites.<\/p>\n<h3>What are the advantages of the recombinant format?<\/h3>\n<p>The recombinant format guarantees <strong>standardization, high reproducibility and elimination of the variations typical of hybridomas<\/strong>.<\/p>\n<h3>Is the product compatible with automation?<\/h3>\n<p>Yes. OncoTrace\u2122 PAX8 is validated for use on <strong>automated IHQ platforms<\/strong> and in manual protocols. <\/p>\n<h3>How to store it?<\/h3>\n<p>Keep between 2\u00b0C and 8\u00b0C. Product stable until expiry date even after opening. <\/p>\n<h2>Confidence in High Complexity Diagnostics<\/h2>\n<p><strong>Ensure precision and reliability in cancer diagnostics with recombinant technology.<\/strong> Request your quote or sample of <strong>OncoTrace\u2122 PAX8 (QR016)<\/strong> now.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>OncoTrace\u2122 PAX8 (QR016) \u2013 Recombinant Antibody for the Diagnosis of Renal, Ovarian, Endometrial and Thyroid Tumors High Specificity in Tumors of M\u00fcllerian, Renal and Thyroid Origin OncoTrace\u2122 PAX8 (Clone QR016) is a recombinant rabbit monoclonal antibody (IgG), developed for the nuclear detection of the PAX8 protein in FFPE tissues. PAX8 belongs to the Paired Box&hellip;<\/p>\n","protected":false},"featured_media":16531,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[771],"product_tag":[751,774,458,460,459,775,773,772],"class_list":{"0":"post-17360","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-oncotrace-recombinant-antibodies","7":"product_tag-antibody","8":"product_tag-clone-en","9":"product_tag-easypath-en","10":"product_tag-ihc","11":"product_tag-immunohistochemistry","12":"product_tag-oncology","13":"product_tag-oncotrace-en","14":"product_tag-recombinant","16":"first","17":"instock","18":"shipping-taxable","19":"purchasable","20":"product-type-variable","21":"col-xs-6 col-sm-4","22":"col-md-3 col-lg-2","23":"un-6-cols"},"_links":{"self":[{"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product\/17360","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/comments?post=17360"}],"version-history":[{"count":0,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product\/17360\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/media\/16531"}],"wp:attachment":[{"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/media?parent=17360"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product_brand?post=17360"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product_cat?post=17360"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product_tag?post=17360"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}