{"id":17360,"date":"2025-08-21T23:13:13","date_gmt":"2025-08-22T02:13:13","guid":{"rendered":"https:\/\/easypath.com.br\/loja\/uncategorized\/oncotrace-pax-8-clone-qr016\/"},"modified":"2026-09-28T08:31:26","modified_gmt":"2026-09-28T11:31:26","slug":"oncotrace-pax-8-clone-qr016","status":"publish","type":"product","link":"https:\/\/easypath.com.br\/en\/produto\/oncotrace-pax-8-clone-qr016\/","title":{"rendered":"Oncotrace PAX-8, Clone QR016"},"content":{"rendered":"<h1>OncoTrace\u2122 PAX8 (QR016) &#8211; Recombinant Antibody for the Diagnosis of Renal, Ovarian, Endometrial and Thyroid Tumors<\/h1>\n<h2>High Specificity in Tumors of M\u00fcllerian, Renal and Thyroid Origin<\/h2>\n<p><strong>OncoTrace\u2122 PAX8 (Clone QR016)<\/strong> is a <strong>recombinant rabbit monoclonal antibody (IgG)<\/strong>, developed for the <strong>nuclear detection of the PAX8 protein<\/strong> in <strong>FFPE<\/strong> tissues. PAX8 belongs to the Paired Box family of transcription factors and is essential in the embryonic development of <strong>kidneys, M\u00fcllerian organs and the thyroid<\/strong>. Its restricted expression makes it a highly sensitive and specific marker for tumors originating in these tissues.  <\/p>\n<h2>Why choose the OncoTrace\u2122 PAX8?<\/h2>\n<ul>\n<li><strong>Critical Marker:<\/strong> PAX8 is present in <strong>ovarian (71-99%)<\/strong>, <strong>thyroid (~90%)<\/strong>, <strong>endometrial (84-98%)<\/strong> and <strong>renal carcinoma (~90%) carcinomas<\/strong>.<\/li>\n<li><strong>High Specificity:<\/strong> Excellent for distinguishing gynecological and renal tumors from metastatic neoplasms from other sites.<\/li>\n<li><strong>Recombinant Production:<\/strong> Stable performance, <strong>no variation between batches<\/strong>.<\/li>\n<li><strong>Compatible with Automation:<\/strong> Validated in manual protocols and automated IHQ platforms.<\/li>\n<li><strong>Cruelty Free:<\/strong> Produced in vitro, without the use of animals.<\/li>\n<\/ul>\n<h2>Diagnostic Applications<\/h2>\n<p><strong>OncoTrace\u2122 PAX8<\/strong> is indicated for the evaluation of tumors of <strong>M\u00fcllerian, renal and thyroid<\/strong> origin, helping to differentiate primary carcinomas of these organs from metastases. It is an essential marker in diagnostic panels for <strong>ovarian, endometrial and renal tumors<\/strong>. <\/p>\n<h2>Comparison: Recombinant vs. hybridoma<\/h2>\n<table style=\"border-collapse: collapse; border: 1px solid black;\" border=\"1\">\n<thead>\n<tr>\n<th>Features<\/th>\n<th>OncoTrace\u2122 Recombinant<\/th>\n<th>Traditional hybridoma<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\n  <strong>Origin<\/strong>\n<\/td>\n<td>Produced in vitro (without animals)<\/td>\n<td>Produced in mice<\/td>\n<\/tr>\n<tr>\n<td>\n  <strong>Reliability<\/strong>\n<\/td>\n<td>Identical performance between batches<\/td>\n<td>Frequent variation<\/td>\n<\/tr>\n<tr>\n<td>\n  <strong>Specificity<\/strong>\n<\/td>\n<td>High affinity, minimal background<\/td>\n<td>Higher risk of cross-reactivity<\/td>\n<\/tr>\n<tr>\n<td>\n  <strong>Standardization<\/strong>\n<\/td>\n<td>Fully controlled<\/td>\n<td>Subject to genetic drift<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Technical Specifications<\/h2>\n<ul>\n<li><strong>Clone:<\/strong> QR016<\/li>\n<li><strong>Host:<\/strong> Rabbit (IgG)<\/li>\n<li><strong>Immunogen:<\/strong> Synthetic peptide of the human protein PAX8<\/li>\n<li><strong>Application:<\/strong> Immunohistochemistry (IHC) on FFPE tissues<\/li>\n<li><strong>Cellular Location:<\/strong> Nuclear<\/li>\n<li><strong>Recommended dilution (Concentrate):<\/strong> 1:100 &#8211; 1:200<\/li>\n<li><strong>Positive Control:<\/strong> Kidney (renal tubules), fallopian tube, endometrium or ovarian carcinoma<\/li>\n<li><strong>Available volumes:<\/strong>\n<ul>\n<li>Concentrate: 0.1 ml, 1 ml<\/li>\n<li>Ready for use: 1 ml, 6 ml<\/li>\n<\/ul>\n<\/li>\n<li><strong>Storage:<\/strong> 2\u00b0C &#8211; 8\u00b0C (stable until expiration date)<\/li>\n<\/ul>\n<h2>Frequently Asked Questions (FAQ)<\/h2>\n<h3>What is the OncoTrace\u2122 PAX8 antibody used for?<\/h3>\n<p>It is used to identify tumors of <strong>M\u00fcllerian, renal and thyroid<\/strong> origin, differentiating them from metastases from other sites.<\/p>\n<h3>What are the advantages of the recombinant format?<\/h3>\n<p>The recombinant format guarantees <strong>standardization, high reproducibility and elimination of the variations typical of hybridomas<\/strong>.<\/p>\n<h3>Is the product compatible with automation?<\/h3>\n<p>Yes. OncoTrace\u2122 PAX8 is validated for use on <strong>automated IHQ platforms<\/strong> and in manual protocols. <\/p>\n<h3>How to store it?<\/h3>\n<p>Keep between 2\u00b0C and 8\u00b0C. Product stable until expiry date even after opening. <\/p>\n<h2>Confidence in High Complexity Diagnostics<\/h2>\n<p><strong>Ensure precision and reliability in cancer diagnostics with recombinant technology.<\/strong> Request your quote or sample of <strong>OncoTrace\u2122 PAX8 (QR016)<\/strong> now.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>OncoTrace\u2122 PAX8 (QR016) &#8211; Recombinant Antibody for the Diagnosis of Renal, Ovarian, Endometrial and Thyroid Tumors High Specificity in Tumors of M\u00fcllerian, Renal and Thyroid Origin OncoTrace\u2122 PAX8 (Clone QR016) is a recombinant rabbit monoclonal antibody (IgG), developed for the nuclear detection of the PAX8 protein in FFPE tissues. PAX8 belongs to the Paired Box&hellip;<\/p>\n","protected":false},"featured_media":16531,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[771],"product_tag":[751,774,458,460,459,775,773,772],"class_list":["post-17360","product","type-product","status-publish","has-post-thumbnail","product_cat-oncotrace-recombinant-antibodies","product_tag-antibody","product_tag-clone-en","product_tag-easypath-en","product_tag-ihc","product_tag-immunohistochemistry","product_tag-oncology","product_tag-oncotrace-en","product_tag-recombinant","first","instock","shipping-taxable","purchasable","product-type-variable","col-xs-6 col-sm-4","col-md-3 col-lg-2","un-6-cols"],"_links":{"self":[{"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product\/17360","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/comments?post=17360"}],"version-history":[{"count":0,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product\/17360\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/media\/16531"}],"wp:attachment":[{"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/media?parent=17360"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product_brand?post=17360"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product_cat?post=17360"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/easypath.com.br\/en\/wp-json\/wp\/v2\/product_tag?post=17360"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}